What is Familial Mediterranean Fever? Familial Mediterranean Fever (FMF) is a rare genetic autoinflammatory disorder characterized by recurrent, self-limiting episodes of fever and inflammation affecting the serous membranes, which line the body cavities such as the lining of the abdomen, chest, and joints. FMF is primarily associated with populations originating …
Read More »Polymyalgia Rheumatica – Description, Complications, and Diagnosis.
Description Polymyalgia rheumatica (PMR) is a disorder that causes muscle pain and stiffness in your neck, shoulders, and hips. It is most common in women and almost always occurs in people over 50. The main symptom is stiffness after resting. Other symptoms include fever, weakness and weight loss. In some …
Read More »Acute Cholecystitis – Description, Causes, and Diagnosis
Description Acute cholecystitis is the most common complication of cholelithiasis. In fact, ≥ 95% of patients with acute cholecystitis have cholelithiasis. When a stone becomes impacted in the cystic duct and persistently obstructs it, acute inflammation results. Bile stasis triggers release of inflammatory enzymes (eg, phospholipase A, which converts lecithin …
Read More »Catarrh – Mechanism, Complications, and Prevention.
What is Catarrh? Catarrh is when mucus accumulates in your nose, throat, or sinuses. The word “catarrh” comes from an ancient Greek phrase meaning “to flow down.” In fact, if you have catarrh, you may feel as if mucus is slowly dripping down the back of your throat. The word …
Read More »Olecranon Bursitis or Elbow Bursitis – Causes and Prevention.
What is olecranon bursitis? Olecranon bursitis causes significant swelling (like a ‘golf ball’) and pain at the back of the elbow. The pain is aggravated by bending the elbow and is particularly painful if you lean on the point of the elbow. The hallmark sign is swelling and this can …
Read More »Psoriatic arthritis – Definition, Risk factors, and Treatment.
What is psoriatic arthritis? Psoriatic arthritis (PsA) is a painful joint condition that complicates the relapsing chronic skin disease psoriasis. It is considered to be an inflammatory joint disorder and is classified as part of the seronegative spondylarthropathies. PsA affects between 5% and 25% of people with psoriasis. It is …
Read More »Behcet’s Disease – Causes, Complication, and Diagnosis.
Introduction Behçet’s (bay-setz) Disease is a rare disease that causes inflammation of many parts of the body. These include the skin of the genital area, lining of the mouth, eye, nervous system, joints and blood vessels. The most characteristic problems include ulcers in the mouth and genital areas, and serious …
Read More »Buerger’s Disease – Pathophysiology, Causes, and Prevention.
Overview – Buerger’s disease Buerger’s disease, also called thromboangiitis obliterans, is an inflammation of small- and medium-sized blood vessels. Although any artery can be affected, it usually presents with blockages of the arteries to the feet and hands, leading to pain and tissue damage. The disease is found worldwide and …
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