Blood Disorders

Cold Agglutinin Disease (CAD) – Types, Causes and Diagnosis

Overview Cold agglutinin disease is a form of autoimmune hemolytic anemia caused by cold-reacting autoantibodies (a type of protein produced by the immune system). Primary cold agglutinin disease is usually associated with monoclonal (produced from a single ancestral cell by repeated cellular replication) cold-reacting autoantibodies. Primary cold agglutinin disease is chronic …

Read More »

Sepsis – Pathophysiology, Treatment, and Prevention.

What is sepsis? Sepsis is a life-threatening illness caused by your body’s response to an infection. Your immune system protects you from many illnesses and infections, but it’s also possible for it to go into overdrive in response to an infection. Sepsis develops when the chemicals the immune system releases …

Read More »

Gangrene – Causes, Symptoms, and Treatment

What is gangrene?   Gangrene, which refers to tissue death caused by a severe shortage of blood supply or serious bacterial infection, occurs in lower extremities. It is more common in the toes than other parts of the body. Gangrene tends to happen more often among people with peripheral artery …

Read More »

Thrombocytopenia – Introduction, Mechanism, and Risk factors.

Introduction People with thrombocytopenia have diminished platelets (Thrombocytes) count in the blood. Platelets are blood cells which help for clotting process. Normal platelets count value is from 150,000 and 450,000 per microliter (one-millionth of a liter). About two-third of platelets are released into the blood stream whereas the remaining are …

Read More »