Human Diseases

What is Castleman Disease? Castleman disease (CD) describes a group of rare disorders that involve enlarged lymph nodes and a broad range of inflammatory symptoms and laboratory abnormalities. The lymph nodes, and the cells that reside in them (lymphocytes and stromal cells), are an integral part of our immune system …

Overview Geographic tongue is a benign condition characterized by inflammation of the tongue (glossitis) that appears in a map-like (geographic) pattern. The normal tongue is covered by a layer of small bumps known as papillae. In affected individuals, certain areas of the tongue are missing these bumps. These affected areas …

Definition Rectocele is a herniation (bulge) of the front wall of the rectum into the back wall of the vagina. The tissue between the rectum and the vagina is known as the rectovaginal septum and this structure can become thin and weak over time, resulting in a rectocele.   When rectoceles …

Definition Glossitis refers to inflammation of the tongue, wherein it displays prominent swelling similar to ulcers on the tongue, apart from unusual colour changes and abnormal texture on its surface. In grave instances, the tongue becomes vastly enlarged, making it difficult to speak clearly and swallow food. The tongue is a vital …

Definition Rhinophyma is a benign condition of the nasal skin that results in abnormal growth and enlargement of the nose. While this is not cancerous, it results in a reddened, “bumpy” appearance of the nose that can be highly disfiguring. The etiology of this condition is multifactorial, but it is …

Definition Peritonsillar abscess, or Quinsy are typically a complication of tonsillitis. They most often are caused by “strep throat” bacteria (group A beta-hemolytic streptococci). The peritonsillar space lies between each tonsil and the wall of the throat. An infection can cause a pus-filled swelling (abscess) to develop in this space. …

Overview Childhood obesity is a complex disease that can occur when your child is above a healthy weight for their age and height. The medical definition of childhood obesity is having a body mass index (BMI) at or above the 95th percentile on the Centers for Disease Control and Prevention’s …

Definition Anal fistula is an abnormal connection or tunnel between two areas in the anorectal region.  The most common cause of anal fistulas is from a blocked mucus gland at the anorectal junction. The gland then becomes inflamed, and in an effort to expel its infected contents, expresses itself, usually …