Bone Disorders

Definition Spondyloarthritis (also known as spondyloarthropathy) is the term which describes the connective tissue diseases. It is the group of inflammatory diseases, including arthritis of the peripheral joints and spine (sacroiliitis or spondylitis); including the area where ligaments and tendons attach to bones (enthesitis or enthesopathy). These diseases cause pain …

Definition Paget’s disease is also known as osteitis deformans and Paget disease. It is a localized disorder occurs during bone remodeling. In this disease, the normal cycle of bone renewal is disrupted due to the abnormal activity of osteoclast cells. Due to which the extreme resorption of bone by osteoclast …

Definition Osteomalacia means soft bones. Bone is a living, active tissue that’s continually being removed and replaced. This process is known as bone turnover. Bone consists of a hard outer shell (the cortex) made up of minerals, mainly calcium and phosphorus, and a softer inner mesh (the matrix) made up …

Definition Rheumatoid arthritis (RA) is an autoimmune disease in which the body’s immune system – which normally protects its health by attacking foreign substances like bacteria and viruses – mistakenly attacks the joints. This creates inflammation that causes the tissue that lines the inside of joints (the synovium) to thicken, …

Definition  Rickets is a bone disorder caused by a deficiency of vitamin D, calcium, or phosphate. Rickets leads to softening and weakening of the bones and is seen most commonly in children 6-24 months of age. Vitamin D promotes the absorption of calcium and phosphorus from the gastrointestinal tract. A …

Definition Osteoporosis is a condition characterized by a decrease in the density of bone, decreasing its strength and resulting in fragile bones. Osteoporosis literally leads to abnormally porous bone that is compressible, like a sponge. This disorder of the skeleton weakens the bone and results in frequent fractures (breaks) in …