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Eastern Equine Encephalitis – Symptoms and Diagnosis

What is Eastern Equine Encephalitis?

Eastern Equine Encephalitis (EEE) is a viral illness that can cause inflammation of the brain. Certain birds are reservoirs for this virus; mosquitoes that feed on these birds can carry the virus to people and other animals. Similar to West Nile Virus and St. Louis Encephalitis, a mosquito that bites an infected bird can in turn bite a mammal or a person. EEE can produce severe disease in horses, some game birds and rarely, people. Most cases of EEE in the United States occur in east coast and gulf coast states.

The Eastern Equine Encephalitis (EEE) virus (togavirus family) has long been recognized in the United States, though fewer than 160 cases have been reported in humans in this country in the past 35 years. However, hundreds of equine cases have been reported in South Carolina, and EEE virus has also been isolated from birds and mosquitoes.

Eastern equine encephalitis virus (electron microscopic image revealed the presence of numerous Eastern equine encephalitis virus virions in this specimen of central nervous system tissue)

How is Eastern Equine Encephalitis spread? (Transmission)

EEEV is transmitted through the bite of an infected mosquito. The primary EEEV vector is a swamp mosquito called the blacktailed mosquito (Culiseta melanura) which transmits the virus to birds, or becomes infected by feeding on infected birds in their swampland habitat. One of the most likely EEE vectors to people is the “cattail mosquito” (Coquilleta perturbans) which breeds in cattail marshes, but disease transmission can come from several other floodwater mosquito species that most commonly occur in coastal or swampy areas. Transmission of the EEE virus does not occur directly from person to person.

Who is at risk of Eastern Equine Encephalitis (EEE) illness?

Signs and Symptoms

Infection causes non-specific clinical signs and often affects the central nervous system.

Diagnosis

If you think you or a family member might have EEE, talk with your health care provider.

Healthcare providers diagnose EEE virus infection based on:

Your healthcare provider can order tests to look for EEE virus infection or other infections that can cause similar symptoms.

Treatment

Prevention of Eastern Equine Encephalitis

How do I protect myself and my family from Eastern Equine Encephalitis (EEE)?

There is no vaccine against EEE virus for humans. Reducing exposure to mosquitoes is the best defense against infection with EEE and other mosquito-borne viruses. There are several approaches you and your family can use to prevent and control mosquito-borne diseases.

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